Vitamin D and Immune Mechanisms of Hypertension in Type 2 Diabetics

Vitamin D and Immune Mechanisms of Hypertension in Type 2 Diabetics

Brief Summary:
This trial will evaluate whether a particular type of circulating white blood cell, monocytes, from type 2 diabetics with high blood pressure and vitamin D deficiency vs. sufficiency will induce hormones that increase blood pressure.

Condition or disease

Diabetes Mellitus, Type 2 Hypertension Vitamin D Deficiency
Diagnostic Test: Blood draw

Detailed Description:
More than half of patients with type 2 diabetes mellitus develop hypertension, which doubles their risk for cardiovascular disease. Inflammation plays a role in the development of these diseases, and monocytes, a type of white blood cell, may be critical. This study will isolate monocytes from blood samples of patients with type 2 diabetes and high blood pressure who have either high levels of vitamin D or low levels of vitamin D, and determine what their effects are on stimulating production in kidney cells of a hormone that increases blood pressure.

Source: View full study details on

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April 26, 2023Comments | Endocrinology Clinical Trials | Endocrinology Studies | US National Library of Medicine