Gastroenterology

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Vaccine Therapy in Treating Patients With Metastatic Solid Tumors
Conditions: Metastatic Breast Cancer; Metastatic Gastrointestinal Carcinoma; HER2-positive Breast Cancer; HER2-positive Gastric Cancer; EGFR Overexpression

Interventions: Biological: Combination of MVF-HER-2 (597-626) and MVF-HER-2 (266-296) emulsified with ISA 720

Sponsors: Pravin T.P Kaumaya

Not yet **RECRUITING NOW**

Source: View full study details on ClinicalTrials.gov

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. By listing a study does not mean it has been evaluated by the U.S. Federal Government. Know the risks and potential benefits of clinical studies and talk to your health care provider before participating. Read our disclaimer for details.

May 16, 2024Comments OffClinicalTrials.gov | Gastroenterology Clinical Trials | Gastroenterology Studies | US National Library of Medicine
A Study of RGX-202-01 (Ompenaclid) as Combination Therapy in RAS Mutant Advanced Colorectal Cancer
Conditions: Gastrointestinal Cancer; Gastrointestinal Neoplasms; Colorectal Cancer; Colorectal Neoplasms; Colorectal Carcinoma; Gastric Cancer; Gastric Neoplasm; KRAS Mutation-Related Tumors; CRC; Colorectal Cancer Metastatic

Interventions: Drug: ompenaclid; Drug: FOLFIRI; Drug: Bevacizumab; Drug: FOLFOX regimen

Sponsors: Inspirna, Inc.

**RECRUITING NOW**

Source: View full study details on ClinicalTrials.gov

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. By listing a study does not mean it has been evaluated by the U.S. Federal Government. Know the risks and potential benefits of clinical studies and talk to your health care provider before participating. Read our disclaimer for details.

May 16, 2024Comments OffClinicalTrials.gov | Gastroenterology Clinical Trials | Gastroenterology Studies | US National Library of Medicine
Nasogastric Decompression Following Pancreaticoduodenectomy
Conditions: Pancreatic Head Neoplasm; Delayed Gastric Emptying; Post Operative Ileus; Whipple Procedure

Interventions: Procedure: pancreaticoduodenectomy

Sponsors: Baylor College of Medicine

Completed

Source: View full study details on ClinicalTrials.gov

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. By listing a study does not mean it has been evaluated by the U.S. Federal Government. Know the risks and potential benefits of clinical studies and talk to your health care provider before participating. Read our disclaimer for details.

May 15, 2024Comments OffClinicalTrials.gov | Gastroenterology Clinical Trials | Gastroenterology Studies | US National Library of Medicine
A Study to Evaluate Sacituzumab Tirumotecan (MK-2870) in Advanced/Metastatic Gastroesophageal Adenocarcinoma (MK-2870-015)
Conditions: Gastroesophageal Cancer

Interventions: Biological: Sacituzumab tirumotecan; Drug: Trifluridine-Tipiracil; Drug: Irinotecan; Drug: Paclitaxel; Drug: Docetaxel

Sponsors: Merck Sharp & Dohme LLC

**RECRUITING NOW**

Source: View full study details on ClinicalTrials.gov

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. By listing a study does not mean it has been evaluated by the U.S. Federal Government. Know the risks and potential benefits of clinical studies and talk to your health care provider before participating. Read our disclaimer for details.

May 14, 2024Comments OffClinicalTrials.gov | Gastroenterology Clinical Trials | Gastroenterology Studies | US National Library of Medicine
Study of Carfilzomib With Irinotecan in Irinotecan-Sensitive Malignancies and Small Cell Lung Cancer Patients
Conditions: Small Cell Lung Carcinoma; Non Small Cell Lung Carcinoma; Irinotecan Sensitive Cancers

Interventions: Drug: Carfilzomib; Drug: Irinotecan

Sponsors: Cancer Research and Biostatistics Clinical Trials Consortium; Lucille P. Markey Cancer Center at University of Kentucky; Washington University School of Medicine

Completed

Source: View full study details on ClinicalTrials.gov

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. By listing a study does not mean it has been evaluated by the U.S. Federal Government. Know the risks and potential benefits of clinical studies and talk to your health care provider before participating. Read our disclaimer for details.

May 10, 2024Comments OffClinicalTrials.gov | Gastroenterology Clinical Trials | Gastroenterology Studies | US National Library of Medicine
Assessment of Esophageal Epithelium Integrity With Use of a Novel Mucosal Impedance Device
Conditions: Gastro Esophageal Reflux

Interventions: Diagnostic Test: single catheter mucosal impedance testing; Diagnostic Test: balloon assembly mucosal impedance testing

Sponsors: Vanderbilt University Medical Center; Sandhill Scientific

Enrolling by invitation

Source: View full study details on ClinicalTrials.gov

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. By listing a study does not mean it has been evaluated by the U.S. Federal Government. Know the risks and potential benefits of clinical studies and talk to your health care provider before participating. Read our disclaimer for details.

May 8, 2024Comments OffClinicalTrials.gov | Gastroenterology Clinical Trials | Gastroenterology Studies | US National Library of Medicine
A Study of NPX267 for Subjects With Solid Tumors Known to Express HHLA2/B7-H7
Conditions: Metastatic Malignant Neoplasm

Interventions: Drug: NPX267

Sponsors: NextPoint Therapeutics, Inc.

**RECRUITING NOW**

Source: View full study details on ClinicalTrials.gov

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. By listing a study does not mean it has been evaluated by the U.S. Federal Government. Know the risks and potential benefits of clinical studies and talk to your health care provider before participating. Read our disclaimer for details.

May 4, 2024Comments OffClinicalTrials.gov | Gastroenterology Clinical Trials | Gastroenterology Studies | US National Library of Medicine
Anticoagulation With Enhanced Gastrointestinal Safety
Conditions: Upper Gastrointestinal Bleeding; Peptic Ulcer Hemorrhage; Anticoagulant-induced Bleeding

Interventions: Behavioral: Clinician Notification with Nurse Facilitation (CNNF); Behavioral: Wait list control

Sponsors: University of Michigan; National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Completed

Source: View full study details on ClinicalTrials.gov

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. By listing a study does not mean it has been evaluated by the U.S. Federal Government. Know the risks and potential benefits of clinical studies and talk to your health care provider before participating. Read our disclaimer for details.

May 1, 2024Comments OffClinicalTrials.gov | Gastroenterology Clinical Trials | Gastroenterology Studies | US National Library of Medicine
Prevalence of Gastric Motor Dysfunction and Upper GI Symptoms in Gastric Antral Vascular Ectasias
Conditions: Gastric Antral Vascular Ectasia; Cirrhosis

Interventions: Diagnostic Test: Gastric Emptying

Sponsors: Mayo Clinic

**RECRUITING NOW**

Source: View full study details on ClinicalTrials.gov

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. By listing a study does not mean it has been evaluated by the U.S. Federal Government. Know the risks and potential benefits of clinical studies and talk to your health care provider before participating. Read our disclaimer for details.

April 27, 2024Comments OffClinicalTrials.gov | Gastroenterology Clinical Trials | Gastroenterology Studies | US National Library of Medicine
Study of Cabozantinib (XL184) in Adults With Advanced Malignancies
Conditions: Solid Tumors; Cancer

Interventions: Drug: Cabozantinib; Drug: Placebo

Sponsors: Exelixis

Completed

Source: View full study details on ClinicalTrials.gov

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. By listing a study does not mean it has been evaluated by the U.S. Federal Government. Know the risks and potential benefits of clinical studies and talk to your health care provider before participating. Read our disclaimer for details.

April 26, 2024Comments OffClinicalTrials.gov | Gastroenterology Clinical Trials | Gastroenterology Studies | US National Library of Medicine