Gastroenterology

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Enzalutamide for Patients With Androgen Receptor Positive Salivary Cancers
Conditions: Androgen Receptor Positive; Locally Advanced Salivary Gland Carcinoma; Metastatic Salivary Gland Carcinoma; Salivary Duct Carcinoma; Salivary Gland Adenocarcinoma, NOS; Salivary Gland Basal Cell Adenocarcinoma; Stage III Major Salivary Gland Cancer AJCC v7

Interventions: Drug: enzalutamide

Sponsors: Alliance for Clinical Trials in Oncology; National Cancer Institute (NCI); Astellas Pharma US, Inc.

Active, not **RECRUITING NOW**

Source: View full study details on ClinicalTrials.gov

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. By listing a study does not mean it has been evaluated by the U.S. Federal Government. Know the risks and potential benefits of clinical studies and talk to your health care provider before participating. Read our disclaimer for details.

October 8, 2026Comments OffClinicalTrials.gov | Gastroenterology Clinical Trials | Gastroenterology Studies | US National Library of Medicine
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EUS-Guided Coil and Glue vs Glue Injection for Bleeding Gastric Varices in Cirrhosis
Conditions: Gastric Varices Bleeding; Cirrhosis

Interventions: Procedure: EUS-guided Coil and Cyanoacrylate Glue Injection; Procedure: Endoscopic Cyanoacrylate Glue Injection

Sponsors: Medanta, The Medicity, India; Orlando Health, Inc.

**RECRUITING NOW**

Source: View full study details on ClinicalTrials.gov

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. By listing a study does not mean it has been evaluated by the U.S. Federal Government. Know the risks and potential benefits of clinical studies and talk to your health care provider before participating. Read our disclaimer for details.

October 3, 2026Comments OffClinicalTrials.gov | Gastroenterology Clinical Trials | Gastroenterology Studies | US National Library of Medicine
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Gastric Focused Ultrasound Stimulation
Conditions: Gastroparesis; Delayed Gastric Emptying

Interventions: Device: Gastric Focused Ultrasound Stimulation

Sponsors: Evan (Huiliang) Wang

**RECRUITING NOW**

Source: View full study details on ClinicalTrials.gov

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. By listing a study does not mean it has been evaluated by the U.S. Federal Government. Know the risks and potential benefits of clinical studies and talk to your health care provider before participating. Read our disclaimer for details.

October 2, 2026Comments OffClinicalTrials.gov | Gastroenterology Clinical Trials | Gastroenterology Studies | US National Library of Medicine
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DBC-664 in Adult Patients With Solid Tumors
Conditions: Malignant Germ Cell Tumor; Lung Adenocarcinoma; Gastric/Esophageal/Gastroesophageal Junction (GEJ) Adenocarcinoma; Urothelial Carcinoma; Endometrial Adenocarcinoma; Ovarian Adenocarcinoma

Interventions: Biological: DBC-664

Sponsors: Duboce Biopharmaceuticals, Inc.

**RECRUITING NOW**

Source: View full study details on ClinicalTrials.gov

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. By listing a study does not mean it has been evaluated by the U.S. Federal Government. Know the risks and potential benefits of clinical studies and talk to your health care provider before participating. Read our disclaimer for details.

September 30, 2026Comments OffClinicalTrials.gov | Gastroenterology Clinical Trials | Gastroenterology Studies | US National Library of Medicine
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Spevatamig (PT886) as Monotherapy or in Combination With Chemo and/or Targeted Therapy and/or ICI, for the Treatment of Patients With Advanced Gastrointestinal Cancers, Including Gastric, Gastroesophageal Junction, Pancreatic Ductal or Biliary Tract Carcinomas (the TWINPEAK Study)
Conditions: Gastric or Gastroesophageal Junction Adenocarcinoma; Pancreatic Ductal Adenocarcinoma; Biliary Tract Cancer (BTC); Colorectal Cancer

Interventions: Drug: Spevatamig (PT886); Drug: Paclitaxel; Drug: Gemcitabine; Drug: Abraxane; Drug: KEYTRUDA® (pembrolizumab); Drug: FOLFOX; Drug: CAPOX; Drug: FOLFIRINOX; Drug: TAS 102; Drug: Bevacizumab; Drug: Gemcitabine Combined With Cisplatin; Drug: NALIRIFOX

Sponsors: Phanes Therapeutics; Merck Sharp & Dohme LLC

**RECRUITING NOW**

Source: View full study details on ClinicalTrials.gov

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. By listing a study does not mean it has been evaluated by the U.S. Federal Government. Know the risks and potential benefits of clinical studies and talk to your health care provider before participating. Read our disclaimer for details.

September 29, 2026Comments OffClinicalTrials.gov | Gastroenterology Clinical Trials | Gastroenterology Studies | US National Library of Medicine
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A Study of 2141-V11 in People With Esophageal, Gastric, or Gastroesophageal Junction Adenocarcinoma
Conditions: Esophageal Cancer; Advanced Esophageal Cancer; Gastric Cancer; Advanced Gastric Cancer; Gastroesophageal Junction Adenocarcinoma; Advanced Gastroesophageal Junction Adenocarcinoma; Esophageal Adenocarcinoma; Gastroesophageal Junction Cancer

Interventions: Biological: Intratumoral 2141-V11; Biological: Nivolumab; Drug: Fluoropyrimidine

Sponsors: Memorial Sloan Kettering Cancer Center; Rockefeller University

**RECRUITING NOW**

Source: View full study details on ClinicalTrials.gov

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. By listing a study does not mean it has been evaluated by the U.S. Federal Government. Know the risks and potential benefits of clinical studies and talk to your health care provider before participating. Read our disclaimer for details.

September 15, 2026Comments OffClinicalTrials.gov | Gastroenterology Clinical Trials | Gastroenterology Studies | US National Library of Medicine
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A Study of ASP2138 Together With Chemotherapy and Pembrolizumab in Adults With Gastric Cancer
Conditions: Gastric Adenocarcinoma; Gastroesophageal Junction (GEJ) Adenocarcinoma

Interventions: Drug: ASP2138; Drug: Pembrolizumab; Drug: Oxaliplatin; Drug: Capecitabine; Drug: Folinic acid; Drug: 5-FU; Drug: Placebo for ASP2138; Drug: Placebo for Pembrolizumab

Sponsors: Astellas Pharma Global Development, Inc.

**RECRUITING NOW**

Source: View full study details on ClinicalTrials.gov

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. By listing a study does not mean it has been evaluated by the U.S. Federal Government. Know the risks and potential benefits of clinical studies and talk to your health care provider before participating. Read our disclaimer for details.

September 12, 2026Comments OffClinicalTrials.gov | Gastroenterology Clinical Trials | Gastroenterology Studies | US National Library of Medicine
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SKL35501 With SKL35502 Imaging in Adults With NTSR1 Positive Advanced Solid Tumors
Conditions: Selected Advanced Solid Tumors; Colorectal Cancer (CRC); Pancreatic Ductal Adenocarcinoma (PDAC); Biliary Tract Cancer (BTC); Gastric Cancer (GC); Esophageal Cancer (EC); Head and Neck Squamous Cell Cancer (HNSCC)

Interventions: Drug: SKL35501; Diagnostic Test: SKL35502

Sponsors: SK Life Science, Inc.

**RECRUITING NOW**

Source: View full study details on ClinicalTrials.gov

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. By listing a study does not mean it has been evaluated by the U.S. Federal Government. Know the risks and potential benefits of clinical studies and talk to your health care provider before participating. Read our disclaimer for details.

September 11, 2026Comments OffClinicalTrials.gov | Gastroenterology Clinical Trials | Gastroenterology Studies | US National Library of Medicine
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Safety and Preliminary Effectiveness of BNT317, an Investigational Therapy for Advanced Solid Tumors
Conditions: Advanced Solid Tumor

Interventions: Biological: BNT317 DL1; Biological: BNT317 DL2; Biological: BNT317 DL3; Biological: BNT317 DL4; Biological: BNT317 DL5; Biological: BNT317 DL6; Biological: BNT317 selected DLA; Biological: BNT317 selected DLB; Drug: SoC chemotherapy 1; Drug: SoC chemotherapy 2

Sponsors: BioNTech SE

**RECRUITING NOW**

Source: View full study details on ClinicalTrials.gov

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. By listing a study does not mean it has been evaluated by the U.S. Federal Government. Know the risks and potential benefits of clinical studies and talk to your health care provider before participating. Read our disclaimer for details.

September 10, 2026Comments OffClinicalTrials.gov | Gastroenterology Clinical Trials | Gastroenterology Studies | US National Library of Medicine
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Phase 1 Study of STRO-006 in Adults With Refractory Solid Tumors That Are Recurrent or Metastatic
Conditions: Head & Neck Squamous Cell Carcinoma; Non-Small Cell Lung Cancer; Esophageal Cancer; Gastric Cancer; Colorectal Cancer; Endometrial Cancer; Urothelial Carcinoma (UC); Breast Cancer

Interventions: Drug: STRO-006; Drug: Pembrolizumab

Sponsors: Sutro Biopharma, Inc.

Not yet **RECRUITING NOW**

Source: View full study details on ClinicalTrials.gov

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. By listing a study does not mean it has been evaluated by the U.S. Federal Government. Know the risks and potential benefits of clinical studies and talk to your health care provider before participating. Read our disclaimer for details.

September 9, 2026Comments OffClinicalTrials.gov | Gastroenterology Clinical Trials | Gastroenterology Studies | US National Library of Medicine
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