Gastroenterology

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A Study of 2141-V11 in People With Esophageal, Gastric, or Gastroesophageal Junction Adenocarcinoma
Conditions: Esophageal Cancer; Advanced Esophageal Cancer; Gastric Cancer; Advanced Gastric Cancer; Gastroesophageal Junction Adenocarcinoma; Advanced Gastroesophageal Junction Adenocarcinoma; Esophageal Adenocarcinoma; Gastroesophageal Junction Cancer

Interventions: Biological: Intratumoral 2141-V11; Biological: Nivolumab; Drug: Fluoropyrimidine

Sponsors: Memorial Sloan Kettering Cancer Center; Rockefeller University

**RECRUITING NOW**

Source: View full study details on ClinicalTrials.gov

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. By listing a study does not mean it has been evaluated by the U.S. Federal Government. Know the risks and potential benefits of clinical studies and talk to your health care provider before participating. Read our disclaimer for details.

September 15, 2026Comments OffClinicalTrials.gov | Gastroenterology Clinical Trials | Gastroenterology Studies | US National Library of Medicine
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A Study of ASP2138 Together With Chemotherapy and Pembrolizumab in Adults With Gastric Cancer
Conditions: Gastric Adenocarcinoma; Gastroesophageal Junction (GEJ) Adenocarcinoma

Interventions: Drug: ASP2138; Drug: Pembrolizumab; Drug: Oxaliplatin; Drug: Capecitabine; Drug: Folinic acid; Drug: 5-FU; Drug: Placebo for ASP2138; Drug: Placebo for Pembrolizumab

Sponsors: Astellas Pharma Global Development, Inc.

**RECRUITING NOW**

Source: View full study details on ClinicalTrials.gov

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. By listing a study does not mean it has been evaluated by the U.S. Federal Government. Know the risks and potential benefits of clinical studies and talk to your health care provider before participating. Read our disclaimer for details.

September 12, 2026Comments OffClinicalTrials.gov | Gastroenterology Clinical Trials | Gastroenterology Studies | US National Library of Medicine
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SKL35501 With SKL35502 Imaging in Adults With NTSR1 Positive Advanced Solid Tumors
Conditions: Selected Advanced Solid Tumors; Colorectal Cancer (CRC); Pancreatic Ductal Adenocarcinoma (PDAC); Biliary Tract Cancer (BTC); Gastric Cancer (GC); Esophageal Cancer (EC); Head and Neck Squamous Cell Cancer (HNSCC)

Interventions: Drug: SKL35501; Diagnostic Test: SKL35502

Sponsors: SK Life Science, Inc.

**RECRUITING NOW**

Source: View full study details on ClinicalTrials.gov

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. By listing a study does not mean it has been evaluated by the U.S. Federal Government. Know the risks and potential benefits of clinical studies and talk to your health care provider before participating. Read our disclaimer for details.

September 11, 2026Comments OffClinicalTrials.gov | Gastroenterology Clinical Trials | Gastroenterology Studies | US National Library of Medicine
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Safety and Preliminary Effectiveness of BNT317, an Investigational Therapy for Advanced Solid Tumors
Conditions: Advanced Solid Tumor

Interventions: Biological: BNT317 DL1; Biological: BNT317 DL2; Biological: BNT317 DL3; Biological: BNT317 DL4; Biological: BNT317 DL5; Biological: BNT317 DL6; Biological: BNT317 selected DLA; Biological: BNT317 selected DLB; Drug: SoC chemotherapy 1; Drug: SoC chemotherapy 2

Sponsors: BioNTech SE

**RECRUITING NOW**

Source: View full study details on ClinicalTrials.gov

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. By listing a study does not mean it has been evaluated by the U.S. Federal Government. Know the risks and potential benefits of clinical studies and talk to your health care provider before participating. Read our disclaimer for details.

September 10, 2026Comments OffClinicalTrials.gov | Gastroenterology Clinical Trials | Gastroenterology Studies | US National Library of Medicine
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Phase 1 Study of STRO-006 in Adults With Refractory Solid Tumors That Are Recurrent or Metastatic
Conditions: Head & Neck Squamous Cell Carcinoma; Non-Small Cell Lung Cancer; Esophageal Cancer; Gastric Cancer; Colorectal Cancer; Endometrial Cancer; Urothelial Carcinoma (UC); Breast Cancer

Interventions: Drug: STRO-006; Drug: Pembrolizumab

Sponsors: Sutro Biopharma, Inc.

Not yet **RECRUITING NOW**

Source: View full study details on ClinicalTrials.gov

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. By listing a study does not mean it has been evaluated by the U.S. Federal Government. Know the risks and potential benefits of clinical studies and talk to your health care provider before participating. Read our disclaimer for details.

September 9, 2026Comments OffClinicalTrials.gov | Gastroenterology Clinical Trials | Gastroenterology Studies | US National Library of Medicine
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A Phase 1/2 Study of BGB-B2033, Alone or in Combination With Tislelizumab With or Without Bevacizumab, in Participants With Advanced or Metastatic Solid Tumors
Conditions: Metastatic Hepatocellular Carcinoma; Local Advanced Hepatocellular Carcinoma; Alpha-fetoprotein (AFP)-Producing Gastric Cancer; Extragonadal Yolk Sac Tumors; Glypican-3 (GPC3)-Positive Squamous Non-small Cell Lung Cancer

Interventions: Drug: BGB-B2033; Drug: Tislelizumab; Drug: Bevacizumab

Sponsors: BeOne Medicines

**RECRUITING NOW**

Source: View full study details on ClinicalTrials.gov

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. By listing a study does not mean it has been evaluated by the U.S. Federal Government. Know the risks and potential benefits of clinical studies and talk to your health care provider before participating. Read our disclaimer for details.

September 9, 2026Comments OffClinicalTrials.gov | Gastroenterology Clinical Trials | Gastroenterology Studies | US National Library of Medicine
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Ph II Intraperitoneal Paclitaxel + System Therapy in GI Ca w/Peritoneal Carcinomatosis (STOPGAP-B)
Conditions: Esophageal Carcinoma; Gastric Cancer (Diagnosis); Colorectal Adenocarcinoma; Appendiceal Adenocarcinoma; Small Bowel Adenocarcinoma; Hepatobiliary Carcinoma in Situ

Interventions: Drug: Paclitaxel Q2W; Drug: Paclitaxcel Q3W

Sponsors: University of California, Irvine

**RECRUITING NOW**

Source: View full study details on ClinicalTrials.gov

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. By listing a study does not mean it has been evaluated by the U.S. Federal Government. Know the risks and potential benefits of clinical studies and talk to your health care provider before participating. Read our disclaimer for details.

September 1, 2026Comments OffClinicalTrials.gov | Gastroenterology Clinical Trials | Gastroenterology Studies | US National Library of Medicine
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Study of Olatorepatide in Adult Participants Living With Overweight or Obesity Without Diabetes
Conditions: Overweight or Obesity

Interventions: Drug: Olatorepatide; Drug: Placebo

Sponsors: Regeneron Pharmaceuticals

**RECRUITING NOW**

Source: View full study details on ClinicalTrials.gov

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. By listing a study does not mean it has been evaluated by the U.S. Federal Government. Know the risks and potential benefits of clinical studies and talk to your health care provider before participating. Read our disclaimer for details.

August 21, 2026Comments OffClinicalTrials.gov | Gastroenterology Clinical Trials | Gastroenterology Studies | US National Library of Medicine
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Identifying Multidimensional Signatures of Gastric Interoception in Functional Dyspepsia
Conditions: Functional Dyspepsia; Anorexia Nervosa

Interventions: Other: Functional magnetic resonance imaging (fMRI)

Sponsors: Massachusetts General Hospital; National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

**RECRUITING NOW**

Source: View full study details on ClinicalTrials.gov

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. By listing a study does not mean it has been evaluated by the U.S. Federal Government. Know the risks and potential benefits of clinical studies and talk to your health care provider before participating. Read our disclaimer for details.

August 20, 2026Comments OffClinicalTrials.gov | Gastroenterology Clinical Trials | Gastroenterology Studies | US National Library of Medicine
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Concurrent Immunotherapy and Systemic Therapy With Stereotactic Body Radiation Therapy (SBRT) for Stage IV Cancers (COINSSS IV)
Conditions: Head and Neck Cancer; Non-Small Cell Lung Cancer; Cervical Cancer; Esophageal Cancer; Gastric Cancer (GC)

Interventions: Radiation: Stereotactic Body Radiation Therapy (SBRT); Drug: Pembrolizumab; Drug: Nivolumab; Drug: Atezolizumab; Drug: Ipilimumab

Sponsors: Mark Bernard

Not yet **RECRUITING NOW**

Source: View full study details on ClinicalTrials.gov

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. By listing a study does not mean it has been evaluated by the U.S. Federal Government. Know the risks and potential benefits of clinical studies and talk to your health care provider before participating. Read our disclaimer for details.

August 19, 2026Comments OffClinicalTrials.gov | Gastroenterology Clinical Trials | Gastroenterology Studies | US National Library of Medicine
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