Ophthalmology

A Study Assessing the Safety, Tolerability, and Efficacy of RO7171009 in Participants With Geographic Atrophy Secondary to Age-Related Macular Degeneration (AMD)

Conditions:   Macular Degeneration, Age-Related;   Geographic Atrophy
Interventions:   Drug: RO7171009;   Drug: Sham Control
Sponsor:   Genentech, Inc.
Recruiting
ClinicalTrials.gov: Ophthalmology | Recruiting, Not yet recruiting, Available Studies | United States | First posted in the last 100 days

June 4, 2019Comments OffAgerelated | Assessing | Atrophy | Degeneration | Efficacy | Geographic | Macular | Participants | RO7171009 | Safety | Secondary | Study | Tolerability
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ReCLAIM-2 Study to Evaluate Safety,Efficacy & Pharmacokinetics of Elamipretide in Subjects With AMD With GA

Condition:   Age-related Macular Degeneration
Interventions:   Combination Product: Subcutaneous elamipretide through the elamipretide delivery system;   Combination Product: Subcutaneos placebo through the elamipretide delivery system
Sponsor:   Stealth BioTherapeutics Inc.
Recruiting
ClinicalTrials.gov: Ophthalmology | Recruiting, Not yet recruiting, Available Studies | United States | First posted in the last 100 days

May 20, 2019Comments OffElamipretide | Evaluate | Pharmacokinetics | ReCLAIM2 | SafetyEfficacy | Study | Subjects
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Azithromycin for Meibomian Gland Disease

Conditions:   Dry Eye;   Neuropathic Eye Pain;   Ocular Microbiome;   Depression, Anxiety
Interventions:   Drug: Azithromycin Oral Product;   Drug: Placebo Oral
Sponsor:   University of California, San Francisco
Not yet recruiting
ClinicalTrials.gov: Ophthalmology | Recruiting, Not yet recruiting, Available Studies | United States | First posted in the last 100 days

May 16, 2019Comments OffAzithromycin | Disease | Gland | Meibomian
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Nailfold Capillary Blood Flow With Latanoprost Bunod

Condition:   Glaucoma, Open-Angle
Interventions:   Drug: Latanoprost 0.005%;   Drug: Latanoprost bunod 0.024%;   Drug: Normal saline 0.9%;   Diagnostic Test: Nailfold capillaroscopy
Sponsor:   Icahn School of Medicine at Mount Sinai
Not yet recruiting
ClinicalTrials.gov: Ophthalmology | Recruiting, Not yet recruiting, Available Studies | United States | First posted in the last 100 days

May 14, 2019Comments OffBlood | Bunod | Capillary | Flow | Latanoprost | Nailfold
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Study of RVT-1401 for the Treatment of Patients With Active, Moderate to Severe Graves’ Ophthalmopathy ( GO )

Condition:   Graves’ Ophthalmopathy (GO)
Interventions:   Drug: RVT-1401 (Administered via subcutaneous injection);   Other: Placebo (Administered via subcutaneous injection)
Sponsor:   Immunovant Sciences GmbH
Not yet recruiting
ClinicalTrials.gov: Ophthalmology | Recruiting, Not yet recruiting, Available Studies | United States | First posted in the last 100 days

May 6, 2019Comments OffActive | Graves' | Moderate | Ophthalmopathy | Patients | RVT1401 | Severe | Study | Treatment
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Study Comparing the Effects of Latanoprostene Bunod and Timolol on Retinal Blood Vessel Density and Visual Acuity

Conditions:   OAG – Open-Angle Glaucoma;   OHT – Ocular Hypertension
Interventions:   Drug: Latanoprostene bunod 0.024% QD;   Drug: Timolol maleate 0.5% BID
Sponsors:   University of California, San Diego;   Bausch & Lomb Incorporated
Recruiting
ClinicalTrials.gov: Ophthalmology | Recruiting, Not yet recruiting, Available Studies | United States | First posted in the last 100 days

April 30, 2019Comments OffAcuity | Blood | Bunod | Comparing | Density | Effects | Latanoprostene | Retinal | Study | Timolol | Vessel | Visual
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A Pilot Study Evaluating Photobiomodulation Therapy for Diabetic Macular Edema

Condition:   Diabetic Macular Edema
Interventions:   Device: Retilux;   Device: Sham Light Device
Sponsors:   Jaeb Center for Health Research;   National Institutes of Health (NIH);   National Eye Institute (NEI);   Juvenile Diabetes Research Foundation;   PhotoOptx LLC
Recruiting
ClinicalTrials.gov: Ophthalmology | Recruiting, Not yet recruiting, Available Studies | United States | First posted in the last 100 days

April 25, 2019Comments OffDiabetic | Edema | Evaluating | Macular | Photobiomodulation | Pilot | Study | Therapy
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