Experimental: ZEN003694 + Talazoparib
ZEN003694: 48.0 mg daily (oral) in 28-day cycles
Talazoparib: 0.75 mg daily (oral) at the same time as ZEN003694
ZEN003694 has shown promising activity in the treatment of solid tumors and hematologic (blood) cancers by reducing the multiplication of cancer cells.
Talazoparib kills cancer cells by inhibiting and trapping the enzyme PARP, which is known to be involved in the development of many types of cancers.
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