Ticagrelor With and Without Aspirin in Patients With Diabetes Mellitus

Ticagrelor With and Without Aspirin in Patients With Diabetes Mellitus

Experimental: Ticagrelor
ticagrelor 60 mg bid monotherapy
Drug: Ticagrelor monotherapy
Eligible patients will enter a 7-10 day run-in phase with aspirin 81 mg/ qd plus ticagrelor 90 mg bid after which they will discontinue aspirin and maintain ticagrelor 90 mg bid monotherapy for 10±3 days. After this period, patients will be randomized using a randomly generated computer sequence in a 1:1:1 fashion to either: a) ticagrelor 60 mg bid monotherapy; b) aspirin 81 mg qd plus ticagrelor 60 mg bid; c) aspirin 81 mg qd plus clopidogrel 75 mg qd. Randomized treatment will be maintained for 10±3 days.
Other Name: Brilinta

Source: View full study details on ClinicalTrials.gov

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June 9, 2023Comments OffClinicalTrials.gov | Endocrinology Clinical Trials | Endocrinology Studies | US National Library of Medicine
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