Spatiotemporal Dimensions of Metabolism in Autochthonous Tumors of GBM Patients

Spatiotemporal Dimensions of Metabolism in Autochthonous Tumors of GBM Patients
Participants in surgery

Surgical removal of the GBM tumor.

Procedure: Surgical removal of the GBM tumor

Surgical removal of the GBM tumor

Other: d4-NAM infusion

Following the surgical removal of the GBM tumor, GBM patients will be dosed with a form of nicotinamide (a natural vitamin) that we can track. The nicotinamide will be converted to methyl nicotinamide (MeNAM) in the tumor. We will measure how fast the nicotinamide is converted to methyl nicotinamide. We believe that the speed of this chemical reaction in the tumor (fast versus slow) may be correlated with GBM aggressiveness.

Other Name: Nicotinamide

Source: View full study details on ClinicalTrials.gov

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September 27, 2023Comments OffClinicalTrials.gov | Oncology Clinical Trials | Oncology Studies | US National Library of Medicine
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