Investigating VIP236 in a dose escalation cohort in subjects with advanced solid tumor cancer
VIP236 is a small molecule drug conjugate (SMDC) consisting of an alpha v beta 3 (αVβ3) integrin binder linked to an optimized camptothecin (CPT) compound (VIP126), which is released by the enzyme neutrophil elastase (NE) in the tumor microenvironment (TME).
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