Multi-agent Low Dose Chemotherapy GAX-CI Followed by Olaparib and Pembro in Metastatic Pancreatic Ductal Cancer.

Multi-agent Low Dose Chemotherapy GAX-CI Followed by Olaparib and Pembro in Metastatic Pancreatic Ductal Cancer.

Brief Summary:
The purpose of this study is to evaluate the safety and clinical activity of maintenance olaparib and pembrolizumab following multi-agent, low dose chemotherapy with gemcitabine, nab-paclitaxel, capecitabine, cisplatin, and irinotecan (GAX-CI) in patients with untreated metastatic pancreatic ductal cancer.

Condition or disease
Intervention/treatment
Phase

Metastatic Pancreatic Cancer
Drug: Nab-paclitaxel Drug: Gemcitabine Drug: Cisplatin Drug: Irinotecan Drug: Capecitabine Drug: Pembrolizumab Drug: Olaparib
Phase 2

Source: View full study details on ClinicalTrials.gov

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March 9, 2023Comments OffClinicalTrials.gov | Endocrinology Clinical Trials | Endocrinology Studies | US National Library of Medicine
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