Ketone Monitoring in T1D: Effect of SGLT2i During Usual Care and With Insulin Deficiency

Ketone Monitoring in T1D: Effect of SGLT2i During Usual Care and With Insulin Deficiency
Group A: Usual care followed by usual care plus dapagliflozin

10 persons with T1D will check capillary beta hydroxybutyrate (BOHB) and concomitant breath acetone (BrAce) 2 – 3 times daily for 2 weeks during usual care, then undergo an insulin withdrawal visit. Subsequently, the Group A patients will repeat the paired measurements of BOHB and BrAce, 2 – 3 times daily for 2 weeks during usual care plus treatment with the SGLT2i dapagliflozin, 10 mg taken orally daily, followed by an insulin withdrawal visit.

Drug: Dapagliflozin 10 MG [Farxiga]

See above.

Device: Biosense Breath Ketone Analyzer

The hand-held device tests ketones in exhaled breath

Source: View full study details on ClinicalTrials.gov

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October 22, 2022Comments OffClinicalTrials.gov | Endocrinology Clinical Trials | Endocrinology Studies | US National Library of Medicine
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