Standard PDT using topical aminolevulinate followed by red light illumination for actinic keratosis. A region of interest (ROI) on the skin of the arms, hands, legs, or feet will be selected for monitoring. This ROI will be marked and baseline measurements will be taken. The topical drug Levulan (ALA) will be applied to the ROI and other areas being treated, and covered with plastic wrap. Prior to red light illumination, post topical measurements and baseline values will be performed to measure PpIX and sO2. Red light illumination will follow, and sO2 phosphorescence will be recorded continuously from the ROI. After, a post-PpIX measurement will be taken.
Topical Levulan Kerastick is applied to actinic keratoses.
- Levulan Kerastick
- Aminolevulinic Acid
Procedure: Photodynamic therapy (PDT)
PDT is a technique that combines a photosensitizing drug and an intense light source to kill tumor cells.
Procedure: Red light illumination
To occur post-PTD; used for activation of ALA during photodynamic therapy.
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