GI-102 Alone or in Combination With Pembrolizumab Before Surgery for the Treatment of Recurrent or Progressive IDH Wildtype Glioblastoma and IDH Mutated Grade 4 Astrocytoma

GI-102 Alone or in Combination With Pembrolizumab Before Surgery for the Treatment of Recurrent or Progressive IDH Wildtype Glioblastoma and IDH Mutated Grade 4 Astrocytoma
Conditions: Glioblastoma, IDH-Wildtype; Progressive Astrocytoma, IDH-Mutant, Grade 4; Progressive Glioblastoma; Progressive Gliosarcoma; Recurrent Astrocytoma, IDH-Mutant, Grade 4; Recurrent Glioblastoma, IDH-Wildtype; Recurrent Gliosarcoma; Resectable Astrocytoma; Resectable Glioblastoma

Interventions: Procedure: Biospecimen Collection; Drug: Bispecific CD80-lgG4Fc-IL-2v Fusion Protein GI-102; Procedure: Computed Tomography; Procedure: Echocardiography Test; Procedure: Magnetic Resonance Imaging; Procedure: Multigated Acquisition Scan; Biological: Pembrolizumab; Procedure: Surgical Procedure

Sponsors: Mayo Clinic

Not yet **RECRUITING NOW**

Source: View full study details on ClinicalTrials.gov

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December 25, 2025Comments OffClinicalTrials.gov | Oncology Clinical Trials | Oncology Studies | US National Library of Medicine
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