Buffered Local Anesthetic

Buffered Local Anesthetic
Experimental: Buffered Anesthetic

Patients will be randomized to one side of the mouth getting the buffered anesthetic and the other side of the mouth to the non-buffered anesthetic.

Drug: Buffered Anesthetic

A cartridge of 2% lidocaine with epinephrine 1:100,000 alkalinized at 9:1 ratio with a resulting pH of 7.21 using 8.4% sodium bicarbonate solution per manufacturer.

Device: Onset

The test solution will be made by a mixing pen called “Onset”- This mixing pen Onset will deliver 0.18 mL of sodium bicarbonate solution into the anesthetic cartridge.

Source: View full study details on ClinicalTrials.gov

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March 8, 2023Comments OffClinicalTrials.gov | Dental Studies | Oncology Clinical Trials | US National Library of Medicine