Experimental: CRD3874-SI
Phase 1a: starting dose of 0.1 mg/kg, Phase 1b: RP2D determined during Phase 1a. Cycle 1 & 2: once weekly infusion x 4 (Days 1, 8, 15, 22) over 28-day cycle. Cycle 3 onwards: weekly infusion x 3 (Days 1, 8, 15) over 28-day cycle
Drug: CRD3874
Starting dose is 0.1 mg/kg for weekly IV infusion of CRD3874-SI.
Cohort CRD3874-SI Dose level (mg/kg)
- 0.1
- 0.3
- 0.9
- 1.8
- 2.7
- 4.05
Source: View full study details on ClinicalTrials.gov
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