A Study of Avutometinib (VS-6766) v. Avutometinib (VS-6766) + Defactinib in Recurrent Low-Grade Serous Ovarian Cancer With and Without a KRAS Mutation

A Study of Avutometinib (VS-6766) v. Avutometinib (VS-6766) + Defactinib in Recurrent Low-Grade Serous Ovarian Cancer With and Without a KRAS Mutation

Experimental: Part A
To determine the optimal regimen, either avutometinib(VS-6766) monotherapy or avutometinib (VS-6766) in combination with defactinib, for subsequent evaluation for efficacy in the Expansion Phase (Part B)
Drug: avutometinib (VS-6766)
avutometinib (VS-6766) Monotherapy
Drug: avutometinib (VS-6766) and Defactinib
avutometinib(VS-6766) and Defactinib Combination
Other Name: avutometinib (VS-6766) and VS-6063

Source: View full study details on ClinicalTrials.gov

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February 18, 2023Comments OffClinicalTrials.gov | Endocrinology Clinical Trials | Endocrinology Studies | US National Library of Medicine
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